What should I do if my computer has been infected by Virus?Last Updated OnOctober 12, 2020 Print You are here: Main Computers how-to What should I do if my computer has been infected by Virus? < All Topics– Disconnect from the Internet. – Reboot your computer into safe mode. – Delete the temporary files(c:\Users\[your user name]\AppData\Local\Temp\). – Run a virus scan. – Delete or quarantine the virus.